There is no life
without RNA

There is no life
without RNA

MAGE Lab logo primary version

A laboratory driven by scientific excellence. Integrated within the GIGA Research Institute in Liège, we bring together researchers, doctoral and post-doctoral students to advance innovative health research.

explore our research

Research at a glance

Publications

0

Active projects

0

Patents

0

Researchers

0

Icône chercheurs en laboratoire
Alumni

0

Scientific research axes

Our research is structured around complementary scientific axes addressing fundamental and translational aspects of biomedical science. Each program integrates multidisciplinary expertise and advanced methodologies.

explore our research

Our research team

Our research team combines multidisciplinary expertise to investigate complex biological processes and translate fundamental insights into meaningful biomedical advances.

Discover the team

Scientific publications

Explore a selection of our recent peer-reviewed journal articles and scientific contributions.

Intrinsic disorder and salt-dependent conformational changes of the N-terminal region of TFIP11 splicing factor

Juniku B., Mignon J., Carême R., Genco A., Obeid A.M., Mottet D.*, Monari A*., Michaux C*.

International Journal of Biological Macromolecules, (2024)

*Authors contributed equally

Read publication

Non-canonical role for the BAF complex subunit in mitosis and ciliogenesis

Verrillo G., Obeid A.M., Genco A., Scrofani J., Ornage F., Hanache S., Mignon J., Leyder T., Michaux C., Kempeneers C., Bricmont N., Herkenne S., Vernos I., Martin M., Mottet D.

Journal of Cell Science, (2024)

Publication highlighted by Journal’s editor :

https://journals.biologists.com/jcs/article/137/9/e137_e0902/347315/A-new-role-for-the-BAF-complex-subunit-DPF3-in

Read publication

Poly(N-methyl-N-vinylacetamide): A Strong Alternative to PEG for Lipid-Based Nanocarriers Delivering siRNA

Berger M., Toussaint F., Ben Djemaa S., Maquoi E., Pendeville H., Evrard B., Jerôme C., Leblong Chain J., Lechanteur A., Mottet D.*, Debuigne A*., Piel G*.

Advanced Healthcare Materials, (2023)

*Authors contributed equally

Publication   selected for the journal's cover

Read publication

Poly(vinyl pyrrolidone) derivatives as PEG alternatives for stealth, non-toxic and less immunogenic siRNA-containing lipoplex delivery

Berger M., Toussaint F., Ben Djemaa S., Laloy J., Pendeville H., Evrard B., Jerôme C., Lechanteur A., Mottet D.*, Debuigne A*., Piel G*. Journal of Controlled Release, (2023)

*Authors contributed equally

Read publication

DHX15-independent roles for TFIP11 in U6 snRNA modification, U4/U6.U5 tri-snRNP assembly and pre-mRNA splicing fidelity

Duchemin A., O’Grady T., Hanache S., Mereau A., Thiry M., Wacheul L., Michaux C., Perpète E.A., Hervouet E. Peixoto P., Ernst F.G.M., Audic Y., Dequiedt F., Lafontaine D.J., Mottet D. Nature Communications, (2021)

Read publication

Metabolic inhibitors accentuates the anti-tumoral effect of HDAC5 inhibition

Hendrick E., Peixoto P., Blomme A., Polese C., Mathéus N., Cimino J., Frère A., Mouithys-Mickalad A., Serteyn D., Bettendorff L., Elmoualij B., De Tullio P., Eppe G., Dequiedt F., Castronovo V., Mottet D. Oncogene, (2017)

Read publication

PEGylated and Functionalized Aliphatic Polycarbonate Polyplex Nanoparticles for Intravenous Administration of HDAC5 siRNA in Cancer Therapy

Frere A., Kawalec M., Tempelaar S., Peixoto P., Hendrick E., Peulen O., Dakwar GR., Diricq J., Dubois P., Evrard B., Remaut K., Braeckmans K., De Smedt SC., Laloy J., Dogné JM., Feller G., Mespouille L., Mottet D*., Piel G*. *Authors contributed equally ACS Appl Mater Interfaces, (2017)

Read publication

Impact of the structure of biocompatible aliphatic polycarbonates on siRNA transfection ability

Frere A., Kawalec M., Tempelaar S., Peixoto P., Hendrick E., Peulen O., Evrard B., Dubois P., Mespouille L*., Mottet D*., Piel G*. *Authors contributed equally Biomacromolecules, (2015)

Read publication

See more

Join the network supporting our research

We collaborate with institutions, foundations and funding entities that share the ambition of advancing impactful biomedical research.

Support our research

Join MAGE Lab

MAGE Lab welcomes applications from motivated researchers, doctoral students and technical staff wishing to contribute to innovative biomedical research.

Starting
January 1, 2026
Postdoctoral Position in RNA Biology
Microscopy image showing cellular components in laboratory researchFluorescent imaging of cells used in biomedical researchMicroscopic image of biological cell sample
Apply
Jobs offer